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1
Applying speech technologies to assess verbal memory in patients with serious mental illness
Abstract: Verbal memory deficits are some of the most profound neurocognitive deficits associated with schizophrenia and serious mental illness in general. As yet, their measurement in clinical settings is limited to traditional tests that allow for limited administrations and require substantial resources to deploy and score. Therefore, we developed a digital ambulatory verbal memory test with automated scoring, and repeated self-administration via smart devices. One hundred and four adults participated, comprising 25 patients with serious mental illness and 79 healthy volunteers. The study design was successful with high quality speech recordings produced to 92% of prompts (Patients: 86%, Healthy: 96%). The story recalls were both transcribed and scored by humans, and scores generated using natural language processing on transcriptions were comparable to human ratings (R = 0.83, within the range of human-to-human correlations of R = 0.73–0.89). A fully automated approach that scored transcripts generated by automatic speech recognition produced comparable and accurate scores (R = 0.82), with very high correlation to scores derived from human transcripts (R = 0.99). This study demonstrates the viability of leveraging speech technologies to facilitate the frequent assessment of verbal memory for clinical monitoring purposes in psychiatry.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066153/
https://doi.org/10.1038/s41746-020-0241-7
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2
24.4 MOVING SPEECH TECHNOLOGY METHODS OUT OF THE LABORATORY: PRACTICAL CHALLENGES AND CLINICAL TRANSLATION OPPORTUNITIES FOR PSYCHIATRY
Holmlund, Terje; Foltz, Peter W; Cohen, Alex S. - : Oxford University Press, 2019
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3
An automated method to analyze language use in patients with schizophrenia and their first-degree relatives
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 23 (2010) 3, 270-284
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OLC Linguistik
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4
An automated method to analyze language use in patients with schizophrenia and their first-degree relatives
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5
Discourse coherence and LSA
In: Handbook of latent semantic analysis (Mahwah, NJ, 2007), p. 167-184
MPI für Psycholinguistik
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6
Helping people find and learn from documents : exploiting synergies between human and computer retrieval with supermanual
In: Handbook of latent semantic analysis (Mahwah, NJ, 2007), p. 323-344
MPI für Psycholinguistik
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7
Automated Communications Analysis System using Latent Semantic Analysis
In: DTIC (2006)
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8
Automated Team Discourse Annotation and Performance Prediction Using LSA
In: DTIC (2004)
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9
Handbook of discourse processes
Singer, Murray (Mitarb.); Alexander, Patricia A. (Mitarb.); Gibbs, Raymond W. (Mitarb.). - Mahwah, NJ : Lawrence Erlbaum, 2003
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UB Frankfurt Linguistik
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10
Content processing with latent semantic analysis : essays, teams and clinical interviews
In: Determination of information and tenor in texts. - Amsterdam : Stichting Neerlandistiek [u.a.] (2003), 179-187
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11
Quantitative Approaches to Semantic Knowledge Representations
In: Discourse processes. - London [u.a.] : Routledge, Taylor and Francis Group 25 (1998) 2-3, 127-130
OLC Linguistik
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12
The Measurement of Textual Coherence With Latent Semantic Analysis
In: Discourse processes. - London [u.a.] : Routledge, Taylor and Francis Group 25 (1998) 2-3, 285-308
OLC Linguistik
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13
An Introduction to Latent Semantic Analysis
In: Discourse processes. - London [u.a.] : Routledge, Taylor and Francis Group 25 (1998) 2-3, 259-284
OLC Linguistik
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14
Learning From Text: Matching Readers and Texts by Latent Semantic Analysis
In: Discourse processes. - London [u.a.] : Routledge, Taylor and Francis Group 25 (1998) 2-3, 309-336
OLC Linguistik
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15
The measurement of textual coherence with latent semantic analysis
In: Quantitative approaches to semantic knowledge representations (New York [etc.], 1998), p. 285-308
MPI für Psycholinguistik
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16
Quantitative approaches to semantic knowledge representations : a special double issue of Discourse Processes
Foltz, Peter W.. - New York [etc.] : Erlbaum, 1998
MPI für Psycholinguistik
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17
An introduction to latent semantic analysis
In: Quantitative approaches to semantic knowledge representations (New York [etc.], 1998), p. 259-284
MPI für Psycholinguistik
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18
Quantitative approaches to semantic knowledge representation
In: Quantitative approaches to semantic knowledge representations (New York [etc.], 1998), p. 127-130
MPI für Psycholinguistik
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19
Sources of comprehension failure : theoretical perspectives and case studies
In: Reading comprehension difficulties (Mahwah, N.J., 1996), p. 137-166
MPI für Psycholinguistik
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